SUCLA2 antibody [N2C3]

Cannot supply to this region.

SKU:: GTX109728
Additional Names:: succinate-CoA ligase ADP-forming beta subunit , A-BETA , A-SCS , MTDPS5 , SCS-betaA
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human SUCLA2. The exact sequence is proprietary.
Clone:: N2C3
Uniprot:: Q9P2R7
Synonyms:: A-BETA;A-SCS;ATP-specific succinyl-CoA synthetase subunit beta;ATP-specific succinyl-CoA synthetase, beta subunit;LINC00444;long intergenic non-protein coding RNA 444;mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta;MTDPS5;renal carcinoma antigen NY-REN-39;SCS-betaA;succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial;succinate-CoA ligase ADP-forming beta subunit;succinate-CoA ligase beta subunit;succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial;succinyl-CoA synthetase beta-A chain
Extra Details:: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]

Shipping Conditions:: Blue Ice