GTX109674
Furin antibody [C3], C-term
Cannot supply to this region.
- SKU:
- GTX109674
- Additional Names:
- furin, paired basic amino acid cleaving enzyme , FUR , PACE , PCSK3 , SPC1
- Application:
- ELISA
- Concentration:
- 0.67 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Furin. The exact sequence is proprietary.
- Clone:
- C3
- Uniprot:
- P09958
- Synonyms:
- dibasic processing enzyme;Dibasic-processing enzyme;FES upstream region;FUR;furin;furin, membrane associated receptor protein;PACE;paired basic amino acid residue-cleaving enzyme;PCSK3;proprotein convertase subtilisin/kexin 3;proprotein convertase subtilisin/kexin type 3;SPC1;subtilisin-like proprotein convertase 1
- Extra Details:
- The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene is thought to play a role in tumor progression. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice