p53R2 antibody [N1C3]

Cannot supply to this region.

SKU:: GTX109620
Additional Names:: ribonucleotide reductase regulatory TP53 inducible subunit M2B , MTDPS8A , MTDPS8B , P53R2
Application:: WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human p53R2. The exact sequence is proprietary.
Clone:: N1C3
Uniprot:: Q7LG56
Synonyms:: MTDPS8A;MTDPS8B;p53-inducible ribonucleotide reductase small subunit 2 homolog;p53-inducible ribonucleotide reductase small subunit 2 short form beta;p53-inducible ribonucleotide reductase small subunit 2-like protein;P53R2;ribonucleoside-diphosphate reductase subunit M2 B;ribonucleotide reductase M2 B (TP53 inducible);TP53-inducible ribonucleotide reductase M2 B
Extra Details:: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Shipping Conditions:: Blue Ice