DNase I antibody [N1C3]

Cannot supply to this region.

SKU:: GTX109306
Additional Names:: deoxyribonuclease 1 , DNL1 , DRNI
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.28 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein corresponding to human DNase I.
Clone:: N1C3
Uniprot:: P24855
Synonyms:: deoxyribonuclease I;deoxyribonuclease-1;DNase I, lysosomal;DNL1;Dornase alfa;DRNI;human urine deoxyribonuclease I
Extra Details:: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]

Shipping Conditions:: Blue Ice