SIGLEC8 antibody [C3], C-term

Cannot supply to this region.

SKU:: GTX108539
Additional Names:: sialic acid binding Ig like lectin 8 , SAF2 , SIGLEC-8 , SIGLEC8L
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.4 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Synthetic peptide encompassing a sequence within the Intracellular domain of human SIGLEC8. The exact sequence is proprietary.
Clone:: C3
Uniprot:: Q9NYZ4
Synonyms:: CDw329;SAF-2;SAF2;sialic acid-binding Ig-like lectin 8;sialoadhesin family member 2;SIGLEC-8;SIGLEC8L
Extra Details:: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM]

Shipping Conditions:: Blue Ice