PAK4 antibody [C1C3]

Cannot supply to this region.

SKU:: GTX107787
Additional Names:: p21 (RAC1) activated kinase 4
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human PAK4. The exact sequence is proprietary.
Clone:: C1C3
Uniprot:: O96013
Synonyms:: p21 protein (Cdc42/Rac)-activated kinase 4;p21-activated kinase 4;p21(CDKN1A)-activated kinase 4;protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs;serine/threonine-protein kinase PAK 4
Extra Details:: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Shipping Conditions:: Blue Ice