GTX107452
TAK1 antibody
Cannot supply to this region.
- SKU:
- GTX107452
- Additional Names:
- mitogen-activated protein kinase kinase kinase 7 , CSCF , FMD2 , MEKK7 , TAK1 , TGF1a
- Application:
- WB
- Concentration:
- 0.2 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human TAK1. The exact sequence is proprietary.
- Uniprot:
- O43318
- Synonyms:
- CSCF;FMD2;MEKK7;mitogen-activated protein kinase kinase kinase 7;TAK1;TGF-beta activated kinase 1;TGF1a;transforming growth factor-beta-activated kinase 1
- Extra Details:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice