ZC3H8 antibody [N1C3]

Cannot supply to this region.

SKU:: GTX107008
Additional Names:: zinc finger CCCH-type containing 8 , Fliz1 , ZC3HDC8
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.84 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.
Clone:: N1C3
Uniprot:: Q8N5P1
Synonyms:: Fliz1;ZC3HDC8;zinc finger CCCH domain-containing protein 8;zinc finger CCCH-type domain containing 8
Extra Details:: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.