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  2. Polyclonal

GTX106380

LXR alpha antibody [C3], C-term

Cannot supply to this region.

SKU:
GTX106380
Additional Names:
nuclear receptor subfamily 1 group H member 3 , LXR-a , LXRA , RLD-1
Application:
WB
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 10% Glycerol, 0.01% Thimerosal.
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LXR alpha. The exact sequence is proprietary.
Clone:
C3
Uniprot:
Q13133
Synonyms:
liver X nuclear receptor alpha variant 1;Liver X receptor alpha;LXR-a;LXRA;Nuclear receptor subfamily 1 group H member 3;oxysterols receptor LXR-alpha;RLD-1
Extra Details:
The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM]
Shipping Conditions:
Blue Ice