GTX10607
Lymphotactin antibody
Cannot supply to this region.
- SKU:
- GTX10607
- Additional Names:
- X-C motif chemokine ligand 1 , ATAC , LPTN , LTN , SCM-1 , SCM-1a , SCM1 , SCM1A , SCYC1
- Application:
- ELISA, WB, Neutralisation
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- purified recombinant human lymphotactin expressed in Escherichia coli.
- Uniprot:
- P47992
- Synonyms:
- ATAC;c motif chemokine 1;chemokine (C motif) ligand 1;cytokine SCM-1;LPTN;LTN;lymphotactin;lymphotaxin;SCM-1;SCM-1-alpha;SCM-1a;SCM1;SCM1A;SCYC1;single cysteine motif 1a;small inducible cytokine subfamily C, member 1 (lymphotactin);small-inducible cytokine C1;XC chemokine ligand 1
- Extra Details:
- Human lymphotactin (Lptn)/XCL1, also named human SCM1 and ATAC, is a member of gamma or C subfamily of chemokines that lack two of the four invariant cysteine residues normally found in the CC and CXC chemokines and have an extended C-terminus. Human lymphotactin encodes a 114 amino acid precursor protein with a 21 amino acid predicted signal peptide. The gene for human and mouse lymphotactin has been mapped to chromosome 1. Human and mouse lymphotactin share approximately 60% amino acid sequence identity.The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other class I MHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Human lymphotactin is chemotactic for lymphocytes and NK cells. Its expression is abundant in some activated T cells such as activated CD8+ T cells and other class I MCH restricted T cells and is absent in CD4+ T cells. It has been shown that lymphotactin is a key regulator of lymphocyte motility and adhesion during acute allograft rejection. The specific receptor for lymphotactin is the orphan receptor XCR1 (GPR5).
- Shipping Conditions:
- Blue Ice