GTX10561
LIMK1 antibody
Cannot supply to this region.
- SKU:
- GTX10561
- Additional Names:
- LIM domain kinase 1 , LIMK , LIMK-1
- Application:
- ELISA, WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to the C-terminal region near aa 620-647 of human LIM kinase protein.
- Uniprot:
- P53667
- Synonyms:
- LIM domain kinase 1;LIM motif-containing protein kinase;LIMK;LIMK-1
- Extra Details:
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified.
- Shipping Conditions:
- Blue Ice