![C2 / C2a antibody [N3C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX105404/GTX105404_40002_IFA_w_23060120_949.webp)
![C2 / C2a antibody [N3C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX105404/GTX105404_WB_w_23060120_277.webp)
GTX105404
C2 / C2a antibody [N3C3]
Cannot supply to this region.
- SKU:
- GTX105404
- Additional Names:
- complement C2 , ARMD14 , CO2
- Application:
- WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Complement C2. The exact sequence is proprietary.
- Clone:
- N3C3
- Uniprot:
- P06681
- Synonyms:
- ARMD14;C3/C5 convertase;CO2;complement C2;complement component 2;complement component C2
- Extra Details:
- Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
- Shipping Conditions:
- Blue Ice