FDPS antibody [N1C3]

Cannot supply to this region.

SKU:: GTX105301
Additional Names:: farnesyl diphosphate synthase , FPPS , FPS , POROK9
Application:: WB, IHC-P, IF, ICC
Concentration:: 1.45 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human FDPS. The exact sequence is proprietary.
Clone:: N1C3
Uniprot:: P14324
Synonyms:: (2E,6E)-farnesyl diphosphate synthase;Dimethylallyltranstransferase;Farnesyl diphosphate synthase;farnesyl pyrophosphate synthase;farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase;FPP synthase;FPP synthetase;FPPS;FPS;Geranyltranstransferase;POROK9
Extra Details:: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Shipping Conditions:: Blue Ice