GTX105168
PLCL1 antibody
Cannot supply to this region.
- SKU:
- GTX105168
- Additional Names:
- phospholipase C like 1 (inactive) , PLCE , PLCL , PLDL1 , PPP1R127 , PRIP
- Application:
- IHC-P
- Concentration:
- 0.92 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human PLCL1. The exact sequence is proprietary.
- Uniprot:
- Q15111
- Synonyms:
- inactive phospholipase C-like protein 1;phospholipase C-deleted in lung carcinoma;phospholipase C-like 1;phospholipase C-related but catalytically inactive protein;phospholipase C, epsilon;PLC-L1;PLCE;PLCL;PLDL1;PPP1R127;PRIP;protein phosphatase 1, regulatory subunit 127
- Extra Details:
- Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
- Shipping Conditions:
- Blue Ice