ADAMTS4 antibody [N3C2], Internal

Cannot supply to this region.

SKU:: GTX105125
Additional Names:: ADAM metallopeptidase with thrombospondin type 1 motif 4 , ADAMTS-2 , ADAMTS-4 , ADMP-1
Application:: WB
Concentration:: 0.33 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human ADAMTS4. The exact sequence is proprietary.
Clone:: N3C2
Uniprot:: O75173
Synonyms:: A disintegrin and metalloproteinase with thrombospondin motifs 4;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4;ADAM-TS 4;ADAM-TS4;ADAMTS-2;ADAMTS-4;ADMP-1;aggrecanase-1;epididymis secretory sperm binding protein
Extra Details:: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq]

Shipping Conditions:: Blue Ice