DUSP14 antibody [C2C3], C-term

Cannot supply to this region.

SKU:: GTX104711
Additional Names:: dual specificity phosphatase 14 , MKP-L , MKP6
Application:: WB
Concentration:: 2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 40% Glycerol, 0.01% Thimerosal.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP14. The exact sequence is proprietary.
Clone:: C2C3
Uniprot:: O95147
Synonyms:: dual specificity protein phosphatase 14;MAP kinase phosphatase 6;mitogen-activated protein kinase phosphatase 6;MKP-1-like protein tyrosine phosphatase;MKP-6;MKP-L;MKP6
Extra Details:: In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM]

Shipping Conditions:: Blue Ice