![NOTCH3 antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX104681/GTX104681_WB_w_23060120_781.webp)
GTX104681
NOTCH3 antibody [C3], C-term
Cannot supply to this region.
- SKU:
- GTX104681
- Additional Names:
- notch receptor 3 , CADASIL , CADASIL1 , CASIL , IMF2 , LMNS
- Application:
- WB
- Concentration:
- 5.26 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Synthetic peptide encompassing a sequence within the Intracellular domain of human Notch3. The exact sequence is proprietary.
- Clone:
- C3
- Uniprot:
- Q9UM47
- Synonyms:
- CADASIL;CADASIL1;CASIL;IMF2;LMNS;neurogenic locus notch homolog protein 3;notch 3;Notch homolog 3
- Extra Details:
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]
- Shipping Conditions:
- Blue Ice