GTX104414
HLA-DPA1 antibody
Cannot supply to this region.
- SKU:
- GTX104414
- Additional Names:
- major histocompatibility complex, class II, DP alpha 1 , DP(W3) , DP(W4) , DPA1 , HLA-DP1A , HLADP , HLASB , PLT1
- Application:
- WB, IHC-P, IHC-Fr, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human HLA-DPA1. The exact sequence is proprietary.
- Uniprot:
- P20036
- Synonyms:
- DP(W3);DP(W4);DPA1;HLA class II histocompatibility antigen, DP alpha 1 chain;HLA DPA1;HLA-DP1A;HLA-DPA;HLA-DPA1*01:03:01:New;HLA-DPA1*02:01:01:NEW;HLA-DPB1;HLA-SB alpha chain;HLADP;HLASB;MHC class II antigen DP alpha chain;MHC class II DP alpha chain;MHC class II DP3-alpha;MHC class II DPA1;MHC class II HLA-DPA1 antigen;MHC class II protein;PLT1
- Extra Details:
- HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice