GTX103925
UHRF1 antibody
Cannot supply to this region.
- SKU:
- GTX103925
- Additional Names:
- ubiquitin like with PHD and ring finger domains 1 , ICBP90 , Np95 , RNF106 , TDRD22 , hNP95 , hUHRF1 , huNp95
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human UHRF1. The exact sequence is proprietary.
- Uniprot:
- Q96T88
- Synonyms:
- E3 ubiquitin-protein ligase UHRF1;hNP95;hUHRF1;huNp95;ICBP90;inverted CCAAT box-binding protein of 90 kDa;Np95;nuclear phosphoprotein 95;nuclear protein 95;nuclear zinc finger protein Np95;RING finger protein 106;RING-type E3 ubiquitin transferase UHRF1;RNF106;TDRD22;transcription factor ICBP90;ubiquitin-like PHD and RING finger domain-containing protein 1;Ubiquitin-like-containing PHD and RING finger domains protein 1
- Extra Details:
- This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice