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  2. Polyclonal

GTX103896

TPP1 antibody

Cannot supply to this region.

SKU:
GTX103896
Additional Names:
tripeptidyl peptidase 1 , CLN2 , GIG1 , LPIC , SCAR7 , TPP-1
Application:
WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TPP1. The exact sequence is proprietary.
Uniprot:
O14773
Synonyms:
cell growth-inhibiting gene 1 protein;CLN2;GIG1;growth-inhibiting protein 1;LPIC;lysosomal pepstatin insensitive protease;lysosomal pepstatin-insensitive carboxypeptidase;Lysosomal pepstatin-insensitive protease;SCAR7;TPP-1;tripeptidyl aminopeptidase;tripeptidyl peptidase I;tripeptidyl-peptidase 1;Tripeptidyl-peptidase I
Extra Details:
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]
Shipping Conditions:
Blue Ice