GTX10383
MIP1 beta antibody
Cannot supply to this region.
- SKU:
- GTX10383
- Additional Names:
- C-C motif chemokine ligand 4 , ACT2 , AT744.1 , G-26 , HC21 , LAG-1 , LAG1 , MIP-1-beta , MIP1B , MIP1B1 , SCYA2 , SCYA4
- Application:
- ELISA, WB, IHC-Fr, Neutralisation
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Purified insect cell line Sf21-derived recombinant human MIP-1beta.
- Uniprot:
- P13236
- Synonyms:
- ACT2;AT744.1;AT744.2;C-C motif chemokine 4;C-C motif chemokine 4-like;CC chemokine ligand 4L1;CCL4L;chemokine (C-C motif) ligand 4;chemokine (C-C motif) ligand 4-like 1, telomeric;G-26;G-26 T-lymphocyte-secreted protein;HC21;LAG-1;LAG1;lymphocyte activation gene 1 protein;macrophage inflammatory protein 1-beta;macrophage inflammatory protein-1b2;MIP-1-beta;MIP-1-beta(1-69);MIP1B;MIP1B1;Monocyte adherence-induced protein 5-alpha;PAT 744;Protein H400;SCYA2;SCYA4;SCYA4L;SCYA4L1;SCYA4L2;secreted protein G-26;SIS-gamma;small inducible cytokine A4 (homologous to mouse Mip-1b);small inducible cytokine A4-like;Small-inducible cytokine A4;Small-inducible cytokine A4-like;T-cell activation protein 2
- Extra Details:
- MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
- Shipping Conditions:
- Blue Ice