FAN antibody [N2C1], Internal

Cannot supply to this region.

SKU:: GTX103723
Additional Names:: neutral sphingomyelinase activation associated factor , FAN , GRAMD5
Application:: WB, IHC-P
Concentration:: 0.93 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human FAN. The exact sequence is proprietary.
Clone:: N2C1
Uniprot:: Q92636
Synonyms:: factor associated with N-SMase activation;factor associated with neutral sphingomyelinase activation;FAN;GRAMD5;neutral sphingomyelinase (N-SMase) activation associated factor;protein FAN
Extra Details:: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.