Seladin 1 antibody [N1C2]

Cannot supply to this region.

SKU:: GTX103712
Additional Names:: 24-dehydrocholesterol reductase , DCE , Nbla03646 , SELADIN1 , seladin-1
Application:: WB, IHC-P, IF, ICC
Concentration:: 1.29 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Rat
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.
Clone:: N1C2
Uniprot:: Q15392
Synonyms:: 24-dehydrocholesterol reductase;3 beta-hydroxysterol delta 24-reductase;3-beta-hydroxysterol Delta-24-reductase;DCE;delta(24)-sterol reductase;desmosterol-to-cholesterol enzyme;diminuto/dwarf1 homolog;Nbla03646;seladin 1;seladin-1;SELADIN1;selective AD indicator 1
Extra Details:: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq]

Shipping Conditions:: Blue Ice