AKAP12 antibody

Cannot supply to this region.

SKU:: GTX10346
Additional Names:: A-kinase anchoring protein 12 , AKAP12A , AKAP12B , AKAP12G
Application:: WB, IP
Physical State:: Liquid
Species Reactivity:: Rat
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Sheep
Reactivities:: Rat
Buffer:: PBS, 0.08% Sodium azide.
Immunogen:: rat SSeCKS.
Uniprot:: Q5QD51
Synonyms:: A kinase (PRKA) anchor protein (gravin) 12;A kinase (PRKA) anchor protein 12;A-kinase anchor protein 12;AKAP-12;AKAP12A;AKAP12B;AKAP12G;SSeCKS, Gravin, AKAP250
Extra Details:: SSeCKS (Src Suppressed C Kinase Substrate) is a major protein kinase C substrate with tumor suppressor activity in models of src- and ras-induced oncogenic transformation. SSeCKS regulates actin-based cytoskeletal and tissue architecture, as well as kinases such as protein kinase C (PKC), protein kinase A (PKA) and calmodulin. Additionally, SSeCKS, has been implicated in the formation of migratory processes and cell migration during embryogenesis. Rat SSeCKS shares extensive homology with human Gravin, an autoantigen in myasthenia gravis that encodes kinase scaffolding functions and whose expression pattern in fibroblasts and nerves suggests a role in cell motility.