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  2. Polyclonal

GTX103314

SLC4A8 antibody [N1N2], N-term

Cannot supply to this region.

SKU:
GTX103314
Additional Names:
solute carrier family 4 member 8 , NBC3 , NDCBE
Application:
WB
Concentration:
0.99 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the Extracellular domain of human SLC4A8. The exact sequence is proprietary.
Clone:
N1N2
Uniprot:
Q2Y0W8
Synonyms:
electroneutral Na(+)-driven Cl-HCO3 exchanger;electroneutral sodium bicarbonate exchanger 1;k-NBC3;NBC3;NDCBE;Solute carrier family 4 member 8;solute carrier family 4, sodium bicarbonate cotransporter, member 8
Extra Details:
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Shipping Conditions:
Blue Ice