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  2. Polyclonal

GTX103229

NBS1 antibody

Cannot supply to this region.

SKU:
GTX103229
Additional Names:
nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95
Application:
WB, IF, ICC, IP
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human NBS1. The exact sequence is proprietary.
Uniprot:
O60934
Synonyms:
AT-V1;AT-V2;ATV;cell cycle regulatory protein p95;NBS;NBS1;nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome protein 1;P95;p95 protein of the MRE11/RAD50 complex
Extra Details:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq]
Shipping Conditions:
Blue Ice