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  2. Polyclonal

GTX10312

ATR antibody

Cannot supply to this region.

SKU:
GTX10312
Additional Names:
ATR , ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
Application:
WB
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Tris-Citrate/Phosphate, 0.1% Sodium azide.
Immunogen:
Synthetic peptide representing a portion of the protein encoded within exon 5 (LocusLink ID 545).
Uniprot:
Q13535
Synonyms:
ataxia telangiectasia and Rad3-related protein;FCTCS;FRAP-related protein 1;FRAP-related protein-1;FRP1;MEC1;MEC1, mitosis entry checkpoint 1, homolog;SCKL;SCKL1;serine/threonine-protein kinase ATR
Extra Details:
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
Shipping Conditions:
Blue Ice