DIAPH3 antibody [C1C3]

Cannot supply to this region.

SKU:: GTX102892
Additional Names:: diaphanous related formin 3 , AN , AUNA1 , DIA2 , DRF3 , NSDAN , diap3 , mDia2
Application:: WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.
Clone:: C1C3
Uniprot:: Q9NSV4
Synonyms:: AN;AUNA1;DIA2;diap3;diaphanous homolog 3;Diaphanous-related formin-3;DRF3;mDia2;NSDAN;protein diaphanous homolog 3
Extra Details:: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.