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  2. Polyclonal

GTX102753

CYP17A1 antibody [N1C2]

Cannot supply to this region.

SKU:
GTX102753
Additional Names:
cytochrome P450 family 17 subfamily A member 1 , CPT7 , CYP17 , P450C17 , S17AH
Application:
WB
Concentration:
0.65 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CYP17A1. The exact sequence is proprietary.
Clone:
N1C2
Uniprot:
P05093
Synonyms:
17-alpha-hydroxyprogesterone aldolase;CPT7;CYP17;CYPXVII;cytochrome P450 17A1;cytochrome p450 XVIIA1;cytochrome P450-C17;cytochrome P450, family 17, subfamily A, polypeptide 1;cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia;cytochrome P450c17;P450C17;S17AH;steroid 17-alpha-hydroxylase/17,20 lyase;steroid 17-alpha-monooxygenase
Extra Details:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]
Shipping Conditions:
Blue Ice