DDR2 antibody [C2C3], C-term

Cannot supply to this region.

SKU:: GTX102651
Additional Names:: discoidin domain receptor tyrosine kinase 2 , MIG20a , NTRKR3 , TKT , TYRO10 , WRCN
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.43 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the Intracellular domain of human DDR2. The exact sequence is proprietary.
Clone:: C2C3
Uniprot:: Q16832
Synonyms:: CD167 antigen-like family member B;cell migration-inducing protein 20;discoidin domain receptor 2;discoidin domain receptor family, member 2;discoidin domain-containing receptor 2;discoidin domain-containing receptor tyrosine kinase 2;hydroxyaryl-protein kinase;MIG20a;migration-inducing gene 16 protein;neurotrophic tyrosine kinase receptor related 3;Neurotrophic tyrosine kinase, receptor-related 3;NTRKR3;receptor protein-tyrosine kinase TKT;TKT;TYRO10;tyrosine-protein kinase TYRO10;WRCN
Extra Details:: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Shipping Conditions:: Blue Ice