RAPGEF5 antibody

Cannot supply to this region.

SKU:: GTX102629
Additional Names:: Rap guanine nucleotide exchange factor 5 , GFR , MR-GEF , REPAC
Application:: WB
Concentration:: 0.74 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human RAPGEF5. The exact sequence is proprietary.
Uniprot:: Q92565
Synonyms:: GFR;guanine nucleotide exchange factor for Rap1;M-Ras-regulated GEF;M-Ras-regulated Rap GEF;MR-GEF;MRGEF;Rap guanine nucleotide exchange factor (GEF) 5;rap guanine nucleotide exchange factor 5;related to Epac;REPAC
Extra Details:: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]