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  2. Polyclonal

GTX102418

BMPR2 antibody [C1C3]

Cannot supply to this region.

SKU:
GTX102418
Additional Names:
bone morphogenetic protein receptor type 2 , BMPR-II , BMPR3 , BMR2 , BRK-3 , POVD1 , PPH1 , T-ALK
Application:
WB
Concentration:
0.17 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the Intracellular domain of human BMPR2. The exact sequence is proprietary.
Clone:
C1C3
Uniprot:
Q13873
Synonyms:
BMP type II receptor;BMP type-2 receptor;BMPR-II;BMPR3;BMR2;bone morphogenetic protein receptor type II;bone morphogenetic protein receptor type-2;bone morphogenetic protein receptor, type II (serine/threonine kinase);BRK-3;POVD1;PPH1;T-ALK;type II activin receptor-like kinase;type II receptor for bone morphogenetic protein-4
Extra Details:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]
Shipping Conditions:
Blue Ice