![Perforin antibody [N1N3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX102379/GTX102379_39742_20240322_WB_TPM_watermark_24032600_729.webp)
GTX102379
Perforin antibody [N1N3]
Cannot supply to this region.
- SKU:
- GTX102379
- Additional Names:
- perforin 1 , HPLH2 , P1 , PFP
- Application:
- WB
- Concentration:
- 0.37 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human Perforin 1. The exact sequence is proprietary.
- Clone:
- N1N3
- Uniprot:
- P14222
- Synonyms:
- cytolysin;HPLH2;lymphocyte pore-forming protein;P1;perforin 1 (pore forming protein);perforin-1;PFP
- Extra Details:
- The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice