TAP antibody [N1N2], N-term

Cannot supply to this region.

SKU:: GTX102071
Additional Names:: nuclear RNA export factor 1 , MEX67 , TAP
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.3 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human TAP. The exact sequence is proprietary.
Clone:: N1N2
Uniprot:: Q9UBU9
Synonyms:: MEX67;mRNA export factor TAP;nuclear RNA export factor 1;TAP;tip associating protein;tip-associated protein;Tip-associating protein
Extra Details:: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Shipping Conditions:: Blue Ice