![EIF3S8 antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101801/GTX101801_40632_WB_w_23060100_131.webp)
GTX101801
EIF3S8 antibody [C2C3], C-term
Cannot supply to this region.
- SKU:
- GTX101801
- Additional Names:
- eukaryotic translation initiation factor 3 subunit C , EIF3CL , EIF3S8 , eIF3-p110
- Application:
- WB
- Concentration:
- 0.9 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human EIF3S8. The exact sequence is proprietary.
- Clone:
- C2C3
- Uniprot:
- Q99613
- Synonyms:
- cell migration-inducing protein 17;eIF3 p110;eIF3-p110;EIF3CL;EIF3S8;eukaryotic translation initiation factor 3 subunit 8;eukaryotic translation initiation factor 3 subunit C;eukaryotic translation initiation factor 3, subunit 8 (110kD);eukaryotic translation initiation factor 3, subunit 8, 110kDa
- Extra Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Shipping Conditions:
- Blue Ice