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  2. Polyclonal

GTX101778

IMPDH2 antibody

Cannot supply to this region.

SKU:
GTX101778
Additional Names:
inosine monophosphate dehydrogenase 2 , IMPD2 , IMPDH-II
Application:
WB, IHC-P, IF, ICC
Concentration:
2 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 40% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IMPDH2. The exact sequence is proprietary.
Uniprot:
P12268
Synonyms:
epididymis secretory sperm binding protein;IMP (inosine 5'-monophosphate) dehydrogenase 2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase II;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH-II;inosine 5' phosphate dehydrogenase 2;inosine monophosphate dehydrogenase type II;inosine-5'-monophosphate dehydrogenase 2;inosine-5'-monophosphate dehydrogenase type II
Extra Details:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq]
Shipping Conditions:
Blue Ice