GTX101774
Septin 2 antibody
Cannot supply to this region.
- SKU:
- GTX101774
- Additional Names:
- septin 2 , DIFF6 , NEDD-5 , NEDD5 , Pnutl3 , hNedd5
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Septin 2. The exact sequence is proprietary.
- Uniprot:
- Q15019
- Synonyms:
- DIFF6;epididymis secretory sperm binding protein;hNedd5;NEDD-5;NEDD5;Neural precursor cell expressed developmentally down-regulated protein 5;neural precursor cell expressed, developmentally down-regulated 5;Pnutl3;SEPT2;septin-2
- Extra Details:
- Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
- Shipping Conditions:
- Blue Ice