![CBL antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101352/GTX101352_39645_IFA_w_23060100_390.webp)
![CBL antibody [C2C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101352/GTX101352_39645_WB_w_23060100_191.webp)
GTX101352
CBL antibody [C2C3], C-term
Cannot supply to this region.
- SKU:
- GTX101352
- Additional Names:
- Cbl proto-oncogene , C-CBL , CBL2 , FRA11B , NSLL , RNF55
- Application:
- WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 40% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human CBL. The exact sequence is proprietary.
- Clone:
- C2C3
- Uniprot:
- P22681
- Synonyms:
- C-CBL;Cas-Br-M (murine) ecotropic retroviral transforming sequence;casitas B-lineage lymphoma proto-oncogene;Cbl proto-oncogene, E3 ubiquitin protein ligase;CBL2;E3 ubiquitin-protein ligase CBL;FRA11B;fragile site, folic acid type, rare, fra(11)(q23.3);NSLL;oncogene CBL2;proto-oncogene c-Cbl;RING finger protein 55;RING-type E3 ubiquitin transferase CBL;RNF55;signal transduction protein CBL
- Extra Details:
- The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice