![CBP antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101249/GTX101249_39721_ChIP_w_23060100_688.webp)
![CBP antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101249/GTX101249_39721_IHC_2_w_23060100_356.webp)
![CBP antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101249/GTX101249_39721_IHC_M_2_w_23060100_758.webp)
![CBP antibody [C3], C-term](https://www.genetex.com/upload/website/prouct_img/normal/GTX101249/GTX101249_39721_IHC_M_3_w_23060100_592.webp)
GTX101249
CBP antibody [C3], C-term
Cannot supply to this region.
- SKU:
- GTX101249
- Additional Names:
- CREB binding protein , CBP , KAT3A , MKHK1 , RSTS , RSTS1
- Application:
- ChIP, WB, IHC-P, IF, ICC, IP
- Concentration:
- 1.6 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human CBP. The exact sequence is proprietary.
- Clone:
- C3
- Uniprot:
- Q92793
- Synonyms:
- CBP;CREB-binding protein;histone lysine acetyltransferase CREBBP;KAT3A;MKHK1;protein-lysine acetyltransferase CREBBP;RSTS;RSTS1
- Extra Details:
- This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice