Factor VII antibody [N3C3]

Cannot supply to this region.

SKU:: GTX101238
Additional Names:: coagulation factor VII , SPCA
Application:: WB
Concentration:: 2.32 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human Factor VII. The exact sequence is proprietary.
Clone:: N3C3
Uniprot:: P08709
Synonyms:: coagulation factor VII;coagulation factor VII (serum prothrombin conversion accelerator);eptacog alfa;FVII coagulation protein;proconvertin;Serum prothrombin conversion accelerator;SPCA
Extra Details:: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq]

Shipping Conditions:: Blue Ice