POR antibody [C2C3], C-term

Cannot supply to this region.

SKU:: GTX101101
Additional Names:: cytochrome p450 oxidoreductase , CPR , CYPOR , P450R
Application:: WB, IHC-P
Concentration:: 0.73 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human POR. The exact sequence is proprietary.
Clone:: C2C3
Uniprot:: P16435
Synonyms:: CPR;CYPOR;NADPH--cytochrome P450 reductase;NADPH--hemoprotein reductase;NADPH-dependent cytochrome P450 reductase;P450 (cytochrome) oxidoreductase;P450R
Extra Details:: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]