GTX100758
RRM1 antibody
Cannot supply to this region.
- SKU:
- GTX100758
- Additional Names:
- ribonucleotide reductase catalytic subunit M1 , R1 , RIR1 , RR1
- Application:
- WB, IHC-P, IF, ICC
- Concentration:
- 0.49 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.
- Uniprot:
- P23921
- Synonyms:
- R1;ribonucleoside-diphosphate reductase large subunit;ribonucleoside-diphosphate reductase subunit M1;Ribonucleotide reductase large subunit;ribonucleotide reductase M1 polypeptide;ribonucleotide reductase, R1 subunit;RIR1;RR1
- Extra Details:
- This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq]
- Shipping Conditions:
- Blue Ice