RASSF1 antibody [N1C3]

Cannot supply to this region.

SKU:: GTX100543
Additional Names:: Ras association domain family member 1 , 123F2 , NORE2A , RASSF1A , RDA32 , REH3P21
Application:: WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human RASSF1. The exact sequence is proprietary.
Clone:: N1C3
Uniprot:: Q9NS23
Synonyms:: 123F2;cardiac-specific ras association domain family 1 protein;NORE2A;pancreas-specific ras association domain family 1 protein;Ras association (RalGDS/AF-6) domain family member 1;ras association domain-containing protein 1;RASSF1A;RDA32;REH3P21;tumor suppressor protein RDA32;WUGSC:H_LUCA12.5
Extra Details:: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Shipping Conditions:: Blue Ice