ESE1 antibody [C2C3], C-term

Cannot supply to this region.

SKU:: GTX100250
Additional Names:: E74 like ETS transcription factor 3 , EPR-1 , ERT , ESE-1 , ESX
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ESE1. The exact sequence is proprietary.
Clone:: C2C3
Uniprot:: P78545
Synonyms:: E74-like factor 3;E74-like factor 3 (ets domain transcription factor, epithelial-specific );E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific);E74-like factor 3 (ets domain transcription factor);epithelial-restricted with serine box;epithelium-restricted Ets protein ESX;epithelium-specific Ets transcription factor 1;EPR-1;ERT;ESE-1;ESX;ets domain transcription factor, serine box (epithelial-specific);ETS-related transcription factor Elf-3
Extra Details:: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.

Shipping Conditions:: Blue Ice