Mre11 antibody [ARC0931]

Cannot supply to this region.

SKU:: GTX05187
Additional Names:: ATLD,HNGS1,MRE11,MRE11 homolog A, double strand break repair nuclease,MRE11A,MRE11B,Mre11,MRE11 homolog, double strand break repair nuclease
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Buffer:: PBS, 0.05% BSA, 50% Glycerol, Proclin300 or sodium azide.
Immunogen:: A synthesized peptide (400-500 aa) derived from human MRE11.
Clone:: ARC0931
Uniprot:: P49959
Synonyms:: AT-like disease;ATLD;DNA recombination and repair protein;double-strand break repair protein MRE11;double-strand break repair protein MRE11A;endo/exonuclease Mre11;HNGS1;meiotic recombination 11 homolog 1;meiotic recombination 11 homolog A;MRE11 double strand break repair nuclease A;MRE11 homolog 1;MRE11 homolog A, double strand break repair nuclease;MRE11 homolog, double strand break repair nuclease A;MRE11 meiotic recombination 11 homolog A;MRE11 meiotic recombination 11-like protein A;MRE11A;MRE11B
Extra Details:: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice