GTX05162
MAN1B1 antibody
Cannot supply to this region.
- SKU:
- GTX05162
- Additional Names:
- ERMAN1,ERManI,MAN1B1,MANAER,MRT15,mannosidase alpha class 1B member 1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.5% BSA, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthesized peptide derived from MAN1B1 at AA range: 100-180
- Uniprot:
- Q9UKM7
- Synonyms:
- endoplasmic Reticulum Class I alpha-mannosidase;endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase;endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1;ER alpha 1,2-mannosidase;ER alpha-1,2-mannosidase;ER mannosidase 1;ERMAN1;ERManI;Man9GlcNAc2-specific processing alpha-mannosidase;Man9GlcNAc2-specific-processing alpha-mannosidase;MANA-ER;Mannosidase alpha class 1B member 1;MRT15
- Extra Details:
- This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
- Shipping Conditions:
- Blue Ice