HLA-ABC antibody [W6/32] (FITC)

Cannot supply to this region.

SKU:: GTX04980-06
Additional Names:: HLAA,major histocompatibility complex, class I, A,AS,B4901,HLAB,major histocompatibility complex, class I, B,D6S204,HLAC,HLAJY3,HLCC,MHC,PSORS1,major histocompatibility complex, class I, C,HLA-C
Application:: Flow Cytometry
Concentration:: 0.1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified by protein G followed by antigen-affinity chromatography.
Storage Conditions:: 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light., -20[o]C Aliquot. Avoid freeze/thaw cycles. Protect from light.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS,1% BSA, 0.09% Sodium azide.
Immunogen:: Purified human tonsil lymphocyte membranes.
Clone:: W6/32
Uniprot:: P01889, P01892, P04439, P10321, P30443, P30450, P30466
Synonyms:: AS;B-4901;D6S204;HLA class I antigen HLA-B;HLA class I histocompatibility antigen, A alpha chain;HLA class I histocompatibility antigen, A-1 alpha chain;HLA class I histocompatibility antigen, B alpha chain;HLA class I histocompatibility antigen, C alpha chain;HLA-C antigen;HLA-Cw;HLA-JY3;HLAA;HLAB;HLAC;HLC-C;Human leukocyte antigen A;Human leukocyte antigen B;Human leukocyte antigen C;human leukocyte antigen-C alpha chain;leukocyte antigen class I-A;leukocyte antigen class I-B;major histocompatibility antigen HLA-C;major histocompatibility complex, class I, B;MHC;MHC class 1 antigen;MHC class I antigen A*1;MHC class I antigen A*2;MHC class I antigen A*26;MHC class I antigen A*3;MHC class I antigen B*18;MHC class I antigen B*7;MHC class I antigen Cw*7;MHC class I antigen heavy chain HLA-C;MHC class I antigen HLA-A heavy chain;MHC class I antigen HLA-B alpha chain;MHC class I antigen HLA-B heavy chain;MHC class I antigen SHCHA;MHC class I molecule;MHC HLA-B cell surface glycoprotein;MHC HLA-B transmembrane glycoprotein;PSORS1
Extra Details:: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]|HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]|HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice