Cytokeratin 5/14 antibody [XM26 + LL002]

Cannot supply to this region.

SKU:: GTX04713
Additional Names:: CK5,DDD,DDD1,EBS2,K5,KRT5,KRT5A,keratin 5,Cytokeratin 5,CK14,EBS3,EBS4,K14,KRT14,NFJ,keratin 14,Cytokeratin 14
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: batch dependent
Immunogen:: XM26: Recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule. LL002: Synthetic peptide of the extreme C-terminal of human keratin-14
Clone:: XM26 + LL002
Uniprot:: P02533, P13647
Synonyms:: 58 kda cytokeratin;CK-5;CK14;CK5;cytokeratin 14;Cytokeratin-14;cytokeratin-5;DDD;DDD1;EBS2;EBS3;EBS4;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K14;K5;keratin 14, type I;keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types);keratin 5, type II;Keratin-14;Keratin-5;keratin, type I cytoskeletal 14;keratin, type II cytoskeletal 5;KRT5A;NFJ;type-II keratin Kb5
Extra Details:: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]|This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice