c-Myc antibody [9E10]

Cannot supply to this region.

SKU:: GTX04712
Additional Names:: MRTL,MYC,MYCC,bHLHe39,cMyc,vmyc avian myelocytomatosis viral oncogene homolog,cmyc,MYC proto-oncogene, bHLH transcription factor
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: batch dependent
Immunogen:: A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLE QLRNSCA) from C-terminus of human c-myc, coupled to KLH 9.
Clone:: 9E10
Uniprot:: P01106
Synonyms:: avian myelocytomatosis viral oncogene homolog;bHLHe39;c-Myc;class E basic helix-loop-helix protein 39;MRTL;myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYCC;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog
Extra Details:: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Shipping Conditions:: Blue Ice