GTX04593
PKC beta 1 (phospho Ser661) antibody
Cannot supply to this region.
- SKU:
- GTX04593
- Additional Names:
- protein kinase C beta , PKC-beta , PKCB , PKCI(2) , PKCbeta , PRKCB1 , PRKCB2
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified; Sequential Chromatography
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% sodium azide.
- Immunogen:
- A synthesized peptide derived from human PRKCB(Accession P05771), corresponding to amino acid residues around phosphorylated Ser661.
- Uniprot:
- P05771
- Synonyms:
- PKC-B;PKC-beta;PKCB;PKCbeta;PKCI(2);PRKCB1;PRKCB2;protein kinase C beta type;protein kinase C, beta 1 polypeptide
- Extra Details:
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice